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A course on Protein Quality Control has been announced, scheduled to take place from June 24 to 27, 2025, just ahead of the EBSA 2025 conference in Rome. The course will take place in Siena.
Purified proteins stand as a central focus in numerous research laboratories, where they are used for a wide spectrum of applications ranging from 3D structural analysis, through X-ray, cryoEM, and NMR studies, to in-depth investigations into interactions (protein-protein, protein-ligand, or protein-nucleic acid) and cell biology experiments. Furthermore, these proteins play a crucial role in characterizing biological (e.g. enzymatic) activities. Beyond the realm of academic research, purified proteins serve as efficient tools in the therapeutic and diagnostic landscape, finding applications in various pharmaceutical industries. To ensure the reliability of experimental data in these studies, stringent protein quality controls are imperative. In 2021, the collaborative efforts of the ARBRE-MOBIEU and P4EU networks resulted in the publication of comprehensive guidelines for evaluating purified proteins in life sciences and medical trials (de Marco et al., 2021; Berrow et al., 2021). The objective of this course is to familiarize participants with these guidelines for protein quality control and to provide an overview of the technologies essential for enhancing the accuracy and reproducibility of data obtained with purified proteins. Throughout the course, participants will have access to the theoretical foundations of these technologies and will also gain hands-on experience with them, ensuring a comprehensive learning experience.
This course is designed for scientists currently using or intending to use purified proteins in their laboratory experiments. By the end of the course, participants should be familiar with a variety of techniques applicable to purified proteins, ultimately enhancing the reliability and reproducibility of data in downstream applications involving these proteins.
The course aims to familiarise participants with guidelines for protein quality control and to provide an overview of technologies essential for enhancing the accuracy and reproducibility of data obtained with purified proteins. Participants will have access to both theoretical foundations and hands-on experience with these technologies, ensuring a comprehensive learning experience.
Comprehensive details, including registration information, can be accessed on the official course website - register here.
The course has been organised in conjunction with the University of Liège, part of Instruct-BE.
