Instruct PartnerRegistration is open for the "Course on Protein Quality Control" from Robotein of Instruct-BE. The course will take place at the University of Liège, Belgium: 28-31 May 2024.
This course is organised by Prof. André Matagne, Laboratory of Enzymology and Protein Folding, Centre for Protein Engineering, University of Liège, Belgium, on behalf of the F.R.S.-FNRS Graduate School “Structure and Function of Biological Macromolecules, Bioinformatics and Modelling” and the Belgian Biophysical Society.
Purified proteins stand as a central focus in numerous research laboratories, where they are used for a wide spectrum of applications ranging from 3D structural analysis, through X-ray, cryo-EM, and NMR studies, to in-depth investigations into interactions (protein-protein, protein-ligand, or protein-nucleic acid) and cell biology experiments. Furthermore, these proteins play a crucial role in characterising biological (e.g. enzymatic) activities. Beyond the realm of academic research, purified proteins serve as efficient tools in the therapeutic and diagnostic landscape, finding applications in various pharmaceutical industries. To ensure the reliability of experimental data in these studies, stringent protein quality controls are imperative. In 2021, the collaborative efforts of the ARBRE-MOBIEU and P4EU networks resulted in the publication of comprehensive guidelines for evaluating purified proteins in life sciences and medical trials (de Marco et al., 2021; Berrow et al., 2021). The objective of this course is to familiarise participants with these guidelines for protein quality control and to provide an overview of the technologies essential for enhancing the accuracy and reproducibility of data obtained with purified proteins. Throughout the course, participants will have access to the theoretical foundations of these technologies and will also gain hands-on experience with them, ensuring a comprehensive learning experience.
This course is designed for scientists currently using or intending to use purified proteins in their laboratory experiments. By the end of the course, participants should be familiar with a variety of techniques applicable to purified proteins, ultimately enhancing the reliability and reproducibility of data in downstream applications involving these proteins.
Find out more about the course and register here by 15 March 2024.
